Whole exome sequencing revealed variants in four genes underlying X-linked intellectual disability in four Iranian families: novel deleterious variants and clinical features with the review of literature

• Main Authors: Atefeh Mir (Author), Yongjun Song (Author), Hane Lee (Author), Hossein Khanahmad (Author), Erfan Khorram (Author), Jafar Nasiri (Author), Mohammad Amin Tabatabaiefar (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim and Objective Intellectual disability (ID) is a heterogeneous condition affecting brain development, function, and/or structure. The X-linked mode of inheritance of ID (X-linked intellectual disability; XLID) has a prevalence of 1 out of 600 to 1000 males. In the last decades, exome seq...