The association between HLA-B variants and amoxicillin-induced severe cutaneous adverse reactions in Chinese han population

• Main Authors: Ting Wang (Author), Jin Yang (Author), Fanping Yang (Author), Ye Cheng (Author), Zichong Huang (Author), Bei Li (Author), Linlin Yang (Author), Qinghe Xing (Author), Xiaoqun Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundAmoxicillin (AMX) is among the most prescribed and the best tolerated antimicrobials worldwide. However, it can occasionally trigger severe cutaneous adverse reactions (SCAR) with a significant morbidity and mortality. The genetic factors that may be relevant to AMX-induced SCAR (AMX-SCAR)...