The association between HLA-B variants and amoxicillin-induced severe cutaneous adverse reactions in Chinese han population

• Автори: Ting Wang (Автор), Jin Yang (Автор), Fanping Yang (Автор), Ye Cheng (Автор), Zichong Huang (Автор), Bei Li (Автор), Linlin Yang (Автор), Qinghe Xing (Автор), Xiaoqun Luo (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

BackgroundAmoxicillin (AMX) is among the most prescribed and the best tolerated antimicrobials worldwide. However, it can occasionally trigger severe cutaneous adverse reactions (SCAR) with a significant morbidity and mortality. The genetic factors that may be relevant to AMX-induced SCAR (AMX-SCAR)...