Cryptosporidium Priming Is More Effective than Vaccine for Protection against Cryptosporidiosis in a Murine Protein Malnutrition Model.

• Egile Nagusiak: Luther A Bartelt (Egilea), David T Bolick (Egilea), Glynis L Kolling (Egilea), James K Roche (Egilea), Edna I Zaenker (Egilea), Ana M Lara (Egilea), Francisco Jose Noronha (Egilea), Carrie A Cowardin (Egilea), John H Moore (Egilea), Jerrold R Turner (Egilea), Cirle A Warren (Egilea), Gregory A Buck (Egilea), Richard L Guerrant (Egilea)
• Formatua: Liburua
• Argitaratua: Public Library of Science (PLoS), 2016-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates clinical features of severe cryptosporidiosis during malnutrition, we interrogated the effect of protein malnutrition (PM) on primary and se...