Ursolic acid reduces oxidative stress injury to ameliorate experimental autoimmune myocarditis by activating Nrf2/HO-1 signaling pathway

• Main Authors: Yanan Fu (Author), Tianshu Liu (Author), Shukun He (Author), Yichan Zhang (Author), Yuting Tan (Author), Ying Bai (Author), Jiawei Shi (Author), Wenhui Deng (Author), Jiani Qiu (Author), Zhen Wang (Author), Yihan Chen (Author), Qiaofeng Jin (Author), Mingxing Xie (Author), Jing Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Oxidative stress is crucial in experimental autoimmune myocarditis (EAM)-induced inflammatory myocardial injury. Ursolic acid (UA) is an antioxidant-enriched traditional Chinese medicine formula. The present study aimed to investigate whether UA could alleviate inflammatory cardiac injur...