17β-Estradiol Promotes Apoptosis of HepG2 Cells Caused by Oxidative Stress by Increasing Foxo3a Phosphorylation

• Main Authors: Yusheng Guo (Author), Xiangsheng Cai (Author), Hanwei Lu (Author), Qiqi Li (Author), Ying Zheng (Author), Zefang Lin (Author), Zexiong Cheng (Author), Maoxiang Yang (Author), Li Zhang (Author), Lei Xiang (Author), Xiaorong Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver cancer is associated with high mortality, particularly in patients infected with the hepatitis B virus. Treatment methods remain very limited. Here, we explored the effects of 17β-estradiol (E2) on apoptosis of various liver cell lines (LO2, HepG2, and HepG2.2.15 cells). Within a certain conce...