Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles

• Main Authors: Patricia Álamo (Author), Victor Pallarès (Author), María Virtudes Céspedes (Author), Aïda Falgàs (Author), Julieta M. Sanchez (Author), Naroa Serna (Author), Laura Sánchez-García (Author), Eric Voltà-Duràn (Author), Gordon A. Morris (Author), Alejandro Sánchez-Chardi (Author), Isolda Casanova (Author), Ramón Mangues (Author), Esther Vazquez (Author), Antonio Villaverde (Author), Ugutz Unzueta (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fluorescent dye labeling is a common strategy to analyze the fate of administered nanoparticles in living organisms. However, to which extent the labeling processes can alter the original nanoparticle biodistribution has been so far neglected. In this work, two widely used fluorescent dye molecules,...