Osteoprotegerin gene polymorphisms and otosclerosis: an additional genetic association study, multilocus interaction and meta-analysis

• Main Authors: Amal Bouzid (Author), Adel Tekari (Author), Fida Jbeli (Author), Amine Chakroun (Author), Kirtal Hansdah (Author), Amal Souissi (Author), Neha Singh (Author), Mohamed Ali Mosrati (Author), Imen Achour (Author), Abdelmonem Ghorbel (Author), Ilhem Charfeddine (Author), Puppala Venkat Ramchander (Author), Saber Masmoudi (Author)
• Format: Book
• Published: BMC, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Otosclerosis (OTSC) is among the most common causes of a late-onset hearing loss in adults and is characterized by an abnormal bone growth in the otic capsule. Alteration in the osteoprotegerin (OPG) expression has been suggested in the implication of OTSC pathogenesis. Methods A...