Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility

• Principais autores: Laith N. AL-Eitan (Autor), Islam M. Al-Dalalah (Autor), Hanan A. Aljamal (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2019-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Pharmacotherapy of epilepsy including antiepileptic drugs (AEDs) is one of the main treatment approaches. As a biological target, sodium channels (Nav channels) and glutamate receptor genes are playing a major role in the etiology and treatment of epilepsy. Objective: This study aims to...