Tetrandrine Citrate Suppresses Breast Cancer via Depletion of Glutathione Peroxidase 4 and Activation of Nuclear Receptor Coactivator 4-Mediated Ferritinophagy

• Main Authors: Jiameng Yin (Author), Yajun Lin (Author), Weiwei Fang (Author), Xin Zhang (Author), Jie Wei (Author), Gang Hu (Author), Pu Liu (Author), Jie Niu (Author), Jun Guo (Author), Yongzhan Zhen (Author), Jian Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tetrandrine citrate (TetC), a novel tetrandrine salt with high water solubility, demonstrates a potent antitumor activity in chronic myeloid leukemia. Studies have indicated an important role of ferroptosis in breast cancer (BC). However, whether TetC inhibits BC progression via ferroptosis has neve...