New Antifungal Compound: Impact of Cosolvency, Micellization and Complexation on Solubility and Permeability Processes

Poor solubility of new antifungal of 1,2,4-triazole class (S-119)-a structural analogue of fluconazole in aqueous media was estimated. The solubility improvement using different excipients: biopolymers (PEGs, PVP), surfactants (Brij S20, pluronic F-127) and cyclodextrins (α-CD, β-CD, 2-HP-β-CD, 6-O-...

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Main Authors: Tatyana V. Volkova (Author), Olga R. Simonova (Author), German L. Perlovich (Author)
Format: Book
Published: MDPI AG, 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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