Formulation, Characterization, and Cytotoxicity Evaluation of Lactoferrin Functionalized Lipid Nanoparticles for Riluzole Delivery to the Brain

• المؤلفون الرئيسيون: Maria Inês Teixeira (مؤلف), Carla Martins Lopes (مؤلف), Hugo Gonçalves (مؤلف), José Catita (مؤلف), Ana Margarida Silva (مؤلف), Francisca Rodrigues (مؤلف), Maria Helena Amaral (مؤلف), Paulo C. Costa (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a very poor prognosis. Its treatment is hindered by a lack of new therapeutic alternatives and the existence of the blood-brain barrier (BBB), which restricts the access of drugs commonly used in ALS, such as riluzole, to the br...