The pseudokinase TRIB3 controls adipocyte lipid homeostasis and proliferation in vitro and in vivo

• Main Authors: Miguel Hernández-Quiles (Author), Laura Martinez Campesino (Author), Imogen Morris (Author), Zabran Ilyas (Author), Steve Reynolds (Author), Nguan Soon Tan (Author), Paula Sobrevals Alcaraz (Author), Edwin C.A. Stigter (Author), Ákos Varga (Author), János Varga (Author), Robert van Es (Author), Harmjan Vos (Author), Heather L. Wilson (Author), Endre Kiss-Toth (Author), Eric Kalkhoven (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: In vivo studies in humans and mice have implicated the pseudokinase Tribbles 3 (TRIB3) in various aspects of energy metabolism. Whilst cell-based studies indicate a role for TRIB3 in adipocyte differentiation and function, it is unclear if and how these cellular functions may contribute t...