Ilicicolin A Exerts Antitumor Effect in Castration-Resistant Prostate Cancer Via Suppressing EZH2 Signaling Pathway

• Main Authors: Lang Guo (Author), Xiaowei Luo (Author), Ping Yang (Author), Yanting Zhang (Author), Jialuo Huang (Author), Hong Wang (Author), Yinfeng Guo (Author), Weifeng Huang (Author), Zhiqiang Chen (Author), Shusheng Wang (Author), Junjian Wang (Author), Jinping Lei (Author), Songtao Xiang (Author), Yonghong Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Polycomb protein enhancer of zeste homolog 2 (EZH2) has critical roles in prostate cancer (PCa) progression and drug-resistance, which remains an obstacle for PCa treatment. Enzalutamide (ENZ) is a second-generation androgen receptor antagonist employed for treatment of metastatic castration-res...