Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent

• Päätekijät: In Yong Bae (Tekijä), Min Sun Choi (Tekijä), Young Seok Ji (Tekijä), Sang-Ku Yoo (Tekijä), Kyungil Kim (Tekijä), Hye Hyun Yoo (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2020-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

HSG4112, a racemic drug, is a new anti-obesity agent. In this study, the stereoselective pharmacokinetics of HSG4112 were investigated in rats and dogs, and the underlying mechanism was investigated. The plasma concentrations of HSG4112(S) and HSG4112(R) were quantitated in plasma from rats and beag...