MYB-NFIB gene fusions identified in archival adenoid cystic carcinoma tissue employing NanoString analysis: an exploratory study

• 主要な著者: John B. McIntyre (著者), Jenny J. Ko (著者), Jodi Siever (著者), Angela M. Y. Chan (著者), Roderick H. W. Simpson (著者), Desiree Hao (著者), Harold Y. Lau (著者)
• フォーマット: 図書
• 出版事項: BMC, 2019-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Adenoid cystic carcinoma (ACC) is a slow growing salivary gland malignancy that is molecularly characterized by t(6:9)(q22-23;p23-24) translocations which predominantly result in MYB-NFIB gene fusions in nearly half of tumours. Detection of MYB-NFIB transcripts is typically perfo...