Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials

• Główni autorzy: Michael J. Iadarola (Autor), Dorothy Cimino Brown (Autor), Alexis Nahama (Autor), Matthew R. Sapio (Autor), Andrew J. Mannes (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

One of the biggest challenges for analgesic drug development is how to decide if a potential analgesic candidate will work in humans. What preclinical data are the most convincing, incentivizing and most predictive of success? Such a predicament is not unique to analgesics, and the pain field has ce...