Clinical Significance of Galactose-Deficient IgA1 by KM55 in Patients with IgA Nephropathy

• Main Authors: Kai Zhang (Author), Qiongqiong Li (Author), Yaru Zhang (Author), Wenya Shang (Author), Li Wei (Author), Hongfen Li (Author), Shan Gao (Author), Tiekun Yan (Author), Junya Jia (Author), Youxia Liu (Author), Shan Lin (Author)
• Format: Book
• Published: Karger Publishers, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Aberrant galactose-deficient IgA1 molecules (Gd-IgA1) are important causal factors in IgA nephropathy (IgAN); however, the detection of Gd-IgA1 in IgAN is complicated and instable. A monoclonal antibody, KM55, which specifically recognizes Gd-IgA1 has been developed. In the present study...