The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK

• 主要な著者: Leopoldo Raul Beltran (著者), Corinna eDawid (著者), Madeline eBeltran (著者), Guenter eGisselmann (著者), Katharina eDegenhardt (著者), Klaus eMathie (著者), Thomas eHofmann (著者), Hanns eHatt (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2013-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

For a long time, the focus of trigeminal chemoperception has rested almost exclusively on TRP channels. However, two-pore domain (K2P) potassium channels have recently been identified as targets for substances associated with typical trigeminal sensations, such as numbing and tingling. In addition,...