TTK is a potential therapeutic target for cisplatin-resistant ovarian cancer

• Main Authors: Yixuan Liu (Author), Keyu Zhu (Author), Xiaolin Guan (Author), Suhong Xie (Author), Yanchun Wang (Author), Ying Tong (Author), Lin Guo (Author), Hui Zheng (Author), Renquan Lu (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Drug resistance and recurrence are main contributors to the poor prognosis of ovarian cancer. Cisplatin is a platinum compound which is widely used in the treatment of various solid tumors including ovarian cancer. Up to now, the mechanism of cisplatin resistance in ovarian cance...