Physiologically Based Pharmacokinetic Modeling of Cefadroxil in Mouse, Rat, and Human to Predict Concentration-Time Profile at Infected Tissue
The aim of this study was to develop physiologically based pharmacokinetic (PBPK) models capable of simulating cefadroxil concentrations in plasma and tissues in mouse, rat, and human. PBPK models in this study consisted of 14 tissues and 2 blood compartments. They were established using measured ti...
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| Main Authors: | , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2021-12-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |