Antianemia Drug Roxadustat (FG-4592) Protects Against Doxorubicin-Induced Cardiotoxicity by Targeting Antiapoptotic and Antioxidative Pathways

Doxorubicin (DOX) is broadly used in treating various malignant tumors. However, its cardiotoxicity limits its clinical use. Roxadustat (FG-4592) is a new hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitor and has been approved for treating anemia in chronic kidney diseases (CKD) patien...

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Main Authors: Guangfeng Long (Author), Hongbing Chen (Author), Mengying Wu (Author), Yuanyuan Li (Author), Ling Gao (Author), Songming Huang (Author), Yue Zhang (Author), Zhanjun Jia (Author), Weiwei Xia (Author)
Format: Book
Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
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