Inference of a causal relation between low-density lipoprotein cholesterol and hypertension using mendelian randomization analysis

• Main Authors: Tae-Hwa Go (Author), Kyeong Im Kwak (Author), Ji-Yun Jang (Author), Minheui Yu (Author), Hye Sim Kim (Author), Jang Young Kim (Author), Sang Baek Koh (Author), Dae Ryong Kang (Author)
• Format: Book
• Published: BMC, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background It is known in some studies that higher the LDL-C, the greater the risk of developing cardiovascular disease. However, studies of the causal effects between LDL-C and hypertension are limited by their observational study design, and genetic epidemiology studies of associations be...