Cux1+ proliferative basal cells promote epidermal hyperplasia in chronic dry skin disease identified by single-cell RNA transcriptomics

• Main Authors: Minhua Huang (Author), Ning Hua (Author), Siyi Zhuang (Author), Qiuyuan Fang (Author), Jiangming Shang (Author), Zhen Wang (Author), Xiaohua Tao (Author), Jianguo Niu (Author), Xiangyao Li (Author), Peilin Yu (Author), Wei Yang (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pathological dry skin is a disturbing and intractable healthcare burden, characterized by epithelial hyperplasia and severe itch. Atopic dermatitis (AD) and psoriasis models with complications of dry skin have been studied using single-cell RNA sequencing (scRNA-seq). However, scRNA-seq analysis of...