Drug Discovery for Overcoming Chronic Kidney Disease (CKD): Prolyl-Hydroxylase Inhibitors to Activate Hypoxia-Inducible Factor (HIF) as a Novel Therapeutic Approach in CKD

Hypoxia-inducible factor (HIF) is a heterodimeric transcription factor composed of an oxygen-dependent α-subunit and constitutively expressed β subunit, which plays a central role in cellular adaptation to hypoxia by transcriptionally upregulating its target genes involved in angiogenesis, erythropo...

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Bibliographic Details
Main Authors: Tetsuhiro Tanaka (Author), Masaomi Nangaku (Author)
Format: Book
Published: Elsevier, 2009-01-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available