Low-Dose Radiation Reduces Doxorubicin-Induced Myocardial Injury Through Mitochondrial Pathways

• Main Authors: Di Zhao (Author), Xin Jiang (Author), Xinxin Meng (Author), Dandan Liu (Author), Yanwei Du (Author), Lijing Zhao (Author), Hongyu Jiang (Author)
• Format: Book
• Published: SAGE Publishing, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The use of doxorubicin (DOX) as an anthraquinone antineoplastic agent is limited due to its cardiotoxicity. Our previous study suggested that low-dose radiation (LDR) could mitigate the cardiotoxicity induced by DOX via suppressing oxidative stress and cell apoptosis. However, the molecular targets...