The Sox2 promoter-driven CD63-GFP transgenic rat model allows tracking of neural stem cell-derived extracellular vesicles

• Main Authors: Aya Yoshimura (Author), Naoki Adachi (Author), Hitomi Matsuno (Author), Masaki Kawamata (Author), Yusuke Yoshioka (Author), Hisae Kikuchi (Author), Haruki Odaka (Author), Tadahiro Numakawa (Author), Hiroshi Kunugi (Author), Takahiro Ochiya (Author), Yoshitaka Tamai (Author)
• Format: Book
• Published: The Company of Biologists, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extracellular vesicles (EVs) can modulate microenvironments by transferring biomolecules, including RNAs and proteins derived from releasing cells, to target cells. To understand the molecular mechanisms maintaining the neural stem cell (NSC) niche through EVs, a new transgenic (Tg) rat strain that...