The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition

• Main Authors: André L. Queiroz (Author), Sarah J. Lessard (Author), Amanda T. Ouchida (Author), Hygor N. Araujo (Author), Dawit A. Gonçalves (Author), Dimitrius Santiago P. Simões Fróes Guimarães (Author), Bruno G. Teodoro (Author), Kawai So (Author), Enilza M. Espreafico (Author), Michael F. Hirshman (Author), Luciane C. Alberici (Author), Isis do Carmo Kettelhut (Author), Laurie J. Goodyear (Author), Leonardo R. Silveira (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: MicroRNAs (miRNA) are known to regulate the expression of genes involved in several physiological processes including metabolism, mitochondrial biogenesis, proliferation, differentiation, and cell death. Methods: Using "in silico" analyses, we identified 219 unique miRNAs that p...