Rapid Target Binding and Cargo Release of Activatable Liposomes Bearing HER2 and FAP Single-Chain Antibody Fragments Reveal Potentials for Image-Guided Delivery to Tumors

• Main Authors: Felista L. Tansi (Author), Ronny Rüger (Author), Claudia Böhm (Author), Frank Steiniger (Author), Martin Raasch (Author), Alexander S. Mosig (Author), Roland E. Kontermann (Author), Ulf K. Teichgräber (Author), Alfred Fahr (Author), Ingrid Hilger (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liposomes represent suitable tools for the diagnosis and treatment of a variety of diseases, including cancers. To study the role of the human epidermal growth factor receptor 2 (HER2) as target in cancer imaging and image-guided deliveries, liposomes were encapsulated with an intrinsically quenched...