In vitro inhibitory effects of ganoderic acid A on human liver cytochrome P450 enzymes

• Main Authors: Shangchen Xu (Author), Fengqing Zhang (Author), Dali Chen (Author), Keren Su (Author), Li Zhang (Author), Rui Jiang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Ganoderic acid A (GAA) is usually used to prevent cancers or other diseases, which make it likely to be used with other drugs metabolized by cytochromes P450. Objective This study investigates the effect of GAA on eight major cytochrome P450 isoforms in human liver microsomes. Material and m...