Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors

Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors

Carbonic anhydrases (CAs, EC 4.2.1.1) are crucial metalloenzymes that are involved in diverse bioprocesses. We report the synthesis and biological evaluation of novel series of benzenesulfonamides incorporating un/substituted ethyl quinoline-3-carboxylate moieties. The newly synthesised compounds we...

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Main Authors: Mohammad M. Al-Sanea (Author), Ahmed Elkamhawy (Author), Sora Paik (Author), Silvia Bua (Author), So Ha Lee (Author), Mohamed A. Abdelgawad (Author), Eun Joo Roh (Author), Wagdy M. Eldehna (Author), Claudiu T. Supuran (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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