A comparative study of the anti-ischemic activity of trimetazidine and the compound ALM-802 under conditions of endothelial dysfunction

• Päätekijät: V. V. Barchukov (Tekijä), I. B. Tsorin (Tekijä), A. M. Likhosherstov (Tekijä), M. B. Vititnova (Tekijä), G. V. Mokrov (Tekijä), S. A. Kryzhanovskii (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: LLC "Publisher OKI", 2019-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Resume. Methods. Acute subendocardial myocardial ischemia in anesthetized rats (urethane 1300 mg/kg, i.p.) was caused by isoproterenol (20 |jg/kg/ min, i.v.). Endothelial dysfunction was induced, causing hyperhomocysteinemia in rats (methionine 3 g/kg intragastrically 1 time per day for 7 days). The...