Lack of μ-Opioid Receptor-Mediated G-Protein Activation in the Spinal Cord of Mice Lacking Exon 1 or Exons 2 and 3 of the MOR-1 Gene

• Hoofdauteurs: Hirokazu Mizoguchi (Auteur), Hsiang-En Wu (Auteur), Minoru Narita (Auteur), Ichiro Sora (Auteur), F. Scott Hall (Auteur), George R. Uhl (Auteur), Horace H. Loh (Auteur), Hiroshi Nagase (Auteur), Leon F. Tseng (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2003-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

ABSTRACT: The G-protein activation induced by μ-opioid receptor agonists was determined in spinal cord membranes from two types of μ-opioid receptor knockout mice: mice with a disruption of exon 1 (MOR (Exon 1)-KO) or exons 2 and 3 (MOR (Exons 2 and 3)-KO) of the μ-opioid receptor gene. The G-protei...