Fluorescence in situ hybridization patterns of BCR/ABL1 fusion in chronic myelogenous leukemia at diagnosis

• Main Authors: Poonam P Jain (Author), Mayur Parihar (Author), Rayaz Ahmed (Author), Aby Abraham (Author), Auro Vishwabandya (Author), Biju George (Author), Vikram Mathews (Author), Alok Srivastava (Author), Vivi M Srivastava (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background : Chronic myelogenous leukemia (CML) is characterised by the t(9;22)(q34;q11.2) which results in the formation of the BCR/ABL1 fusion gene. Occasionally, the t(9;22) may be associated with submicroscopic deletions of chromosomes 9 and/or 22 which appear to be associated with a worse progn...