Growth hormone secretagogue receptor‐1a mediates ghrelin's effects on attenuating tumour‐induced loss of muscle strength but not muscle mass

• Main Authors: Haiming Liu (Author), Pu Zang (Author), Ian (In‐gi) (Author), Barbara Anderson (Author), Anthony Christiani (Author), Lena Strait‐Bodey (Author), Beatrice A. Breckheimer (Author), Mackenzie Storie (Author), Alison Tewnion (Author), Kora Krumm (Author), Theresa Li (Author), Brynn Irwin (Author), Jose M. Garcia (Author)
• Format: Book
• Published: Wiley, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ghrelin may ameliorate cancer cachexia (CC) by preventing anorexia, muscle, and fat loss. However, the mechanisms mediating these effects are not fully understood. This study characterizes the pathways involved in muscle mass and strength loss in the Lewis lung carcinoma (LLC)‐in...