The epidemiology of sickle cell disease in children recruited in infancy in Kilifi, Kenya: a prospective cohort study

• Main Authors: Sophie Uyoga, PhD (Author), Alex W Macharia, MSc (Author), George Mochamah, MSc (Author), Carolyne M Ndila, PhD (Author), Gideon Nyutu, BSc (Author), Johnstone Makale, BSc (Author), Metrine Tendwa, BSc (Author), Emily Nyatichi, BSc (Author), John Ojal, PhD (Author), Mark Otiende, MSc (Author), Mohammed Shebe, DipMed (Author), Kennedy O Awuondo, BSc (Author), Neema Mturi, MMed (Author), Norbert Peshu, MMed (Author), Benjamin Tsofa, MMed (Author), Kathryn Maitland, ProfFMedSci (Author), J Anthony G Scott, ProfFMedSci (Author), Thomas N Williams, ProfFMedSci (Author)
• Format: Book
• Published: Elsevier, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Sickle cell disease is the most common severe monogenic disorder in humans. In Africa, 50-90% of children born with sickle cell disease die before they reach their fifth birthday. In this study, we aimed to describe the comparative incidence of specific clinical outcomes among c...