Optimizing gefitinib nanoliposomes by Box-Behnken design and coating with chitosan: A sequential approach for enhanced drug delivery

• Main Authors: Seema Rohilla (Author), Rajendra Awasthi (Author), Ankur Rohilla (Author), Sachin Kumar Singh (Author), Dinesh Kumar Chellappan (Author), Kamal Dua (Author), Harish Dureja (Author)
• Format: Book
• Published: International Association of Physical Chemists (IAPC), 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to improve the stability and prolonged gefitinib release from the nanoliposomes. Nanoliposomes were prepared by reverse-phase evaporation and optimized using Box-Behnken design to investigate the influence of sonication time (X1), tween 80 / soya phosphatidylcholine ratio (X2), and...