A facile and universal method to achieve liposomal remote loading of non-ionizable drugs with outstanding safety profiles and therapeutic effect

• Main Authors: Shuang Zhou (Author), Jinbo Li (Author), Jiang Yu (Author), Liyuan Yang (Author), Xiao Kuang (Author), Zhenjie Wang (Author), Yingli Wang (Author), Hongzhuo Liu (Author), Guimei Lin (Author), Zhonggui He (Author), Dan Liu (Author), Yongjun Wang (Author)
• Format: Book
• Published: Elsevier, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liposomes have made remarkable achievements as drug delivery vehicles in the clinic. Liposomal products mostly benefited from remote drug loading techniques that succeeded in amphipathic and/or ionizable drugs, but seemed impracticable for nonionizable and poorly water-soluble therapeutic agents, th...