A Theranostic Small-Molecule Prodrug Conjugate for Neuroendocrine Prostate Cancer

• Главные авторы: Paulina Gonzalez (Автор), Sashi Debnath (Автор), Yu-An Chen (Автор), Elizabeth Hernandez (Автор), Preeti Jha (Автор), Marianna Dakanali (Автор), Jer-Tsong Hsieh (Автор), Xiankai Sun (Автор)
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• Опубликовано: MDPI AG, 2023-02-01T00:00:00Z.
• Предметы: article
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After androgen deprivation therapy, a significant number of prostate cancer cases progress with a therapy-resistant neuroendocrine phenotype (NEPC). This represents a challenge for diagnosis and treatment. Based on our previously reported design of theranostic small-molecule prodrug conjugates (T-SM...