Anti-Tuberculosis Activity of Three Carbapenems, Clofazimine and Nitazoxanide Using a Novel Ex Vivo Phenotypic Drug Susceptibility Model of Human Tuberculosis

• Principais autores: Ximena Gonzalo (Autor), Magdalena K. Bielecka (Autor), Liku Tezera (Autor), Paul Elkington (Autor), Francis Drobniewski (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2022-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

We evaluated a novel physiological 3-D bioelectrospray model of the tuberculosis (TB) granuloma to test the activity of a known anti-TB drug, clofazimine; three carbapenems with potential activity, including one currently used in therapy; and nitazoxanide, an anti-parasitic compound with possible TB...