Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni-- 'the undiscovered country'.

• Main Authors: Martin Horn (Author), Pavla Fajtová (Author), Liliana Rojo Arreola (Author), Lenka Ulrychová (Author), Pavla Bartošová-Sojková (Author), Zdeněk Franta (Author), Anna V Protasio (Author), David Opavský (Author), Jiří Vondrášek (Author), James H McKerrow (Author), Michael Mareš (Author), Conor R Caffrey (Author), Jan Dvořák (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Blood flukes (Schistosoma spp.) are parasites that can survive for years or decades in the vasculature of permissive mammalian hosts, including humans. Proteolytic enzymes (proteases) are crucial for successful parasitism, including aspects of invasion, maturation and reproduction. Most attention ha...