Loss of protein kinase D activity demonstrates redundancy in cardiac glucose metabolism and preserves cardiac function in obesity

• Main Authors: Kirstie A. De Jong (Author), Liam G. Hall (Author), Mark C. Renton (Author), Timothy Connor (Author), Sheree D. Martin (Author), Greg M. Kowalski (Author), Christopher S. Shaw (Author), Clinton R. Bruce (Author), Kirsten F. Howlett (Author), Sean L. McGee (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Protein kinase D (PKD) signaling has been implicated in stress-induced cardiac remodeling and function as well as metabolic processes including contraction-mediated cardiac glucose uptake. PKD has recently emerged as a nutrient-sensing kinase that is activated in high-lipid environments,...