POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction

Abstract Background The morbidity and mortality of endometrial tumors, a common type of malignant cancer in women, have increased in recent years. POLE encodes the DNA polymerase ε, which is responsible for the leading strand DNA replication. Somatic mutations of POLE have been acknowledged in numer...

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Main Authors: Yiran Li (Author), Yiding Bian (Author), Kai Wang (Author), Xiao-Ping Wan (Author)
Format: Book
Published: BMC, 2019-12-01T00:00:00Z.
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3rd Floor Main Library

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