Development of a Simple and Quick Method to Assess Base Editing in Human Cells

• Main Authors: Xiujuan Lv (Author), Kairui Qiu (Author), Tianxiang Tu (Author), Xiaoxue He (Author), Yuchen Peng (Author), Jinbin Ye (Author), Junhao Fu (Author), Ruzhi Deng (Author), Yuqin Wang (Author), Jinyu Wu (Author), Changbao Liu (Author), Junzhao Zhao (Author), Feng Gu (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Base editing is a form of genome editing that can directly convert a single base (C or A) to another base (T or G), which is of great potential in biomedical applications. The broad application of base editing is limited by its low activity and specificity, which still needs to be resolved. To addre...