SLC35B4 Stabilizes c-MYC Protein by O-GlcNAcylation in HCC

• Main Authors: Tao Jiang (Author), Jinghong Yang (Author), Huohong Yang (Author), Wancheng Chen (Author), Kaiyuan Ji (Author), Yang Xu (Author), Lili Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

UDP-GlcNAc is a sugar substrate necessary for the O-GlcNAcylation of proteins. SLC35B4 is one of the nucleotide sugar transporters that transport UDP-GlcNAc and UDP-xylose into the endoplasmic reticulum and Golgi apparatus for glycosylation. The roles of SLC35B4 in hepatocellular carcinoma (HCC) tum...