Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Tadalafil in Colorectal Cancer

• Main Authors: Pan Zhao (Author), Yao Shen (Author), Mengyang Li (Author), Hanjun Dan (Author), Zhiming Zhao (Author), Jian Zhang (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

The potential role of tadalafil, a PDE5 inhibitor, in anticancer activity and prolonged survival has been proposed. However, the systematic effects of tadalafil in colorectal cancer were not fully understood. In this study, we assessed the anti-tumor activity of tadalafil in human colorectal cancer...