Inhibition of IKKβ/NF-κB signaling facilitates tendinopathy healing by rejuvenating inflamm-aging induced tendon-derived stem/progenitor cell senescence

• Main Authors: Chongyang Wang (Author), Zhekun Zhou (Author), Wei Song (Author), Zhuochang Cai (Author), Zhenyu Ding (Author), Daoyun Chen (Author), Fangfang Xia (Author), Yaohua He (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Degenerative rotator cuff tendinopathy (RCT) is a chronic tendon disease caused by degeneration and inflammation, which often affects the elderly population. Mesenchymal stem cell senescence is generally recognized as an important pathophysiological mechanism in many age-related skeletal diseases. H...