Modulating intestinal mucus barrier for nanoparticles penetration by surfactants

• Autores principales: Xin Zhang (Autor), Wei Dong (Autor), Hongbo Cheng (Autor), Meixia Zhang (Autor), Yongqiang Kou (Autor), Jian Guan (Autor), Qiaoyu Liu (Autor), Mingyue Gao (Autor), Xiuhua Wang (Autor), Shirui Mao (Autor)
• Formato: Libro
• Publicado: Elsevier, 2019-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Improving peroral delivery efficiency is always a persistent goal for both small-molecule and macromolecular drug development. However, intestinal mucus barrier which greatly impedes drug-loaded nanoparticles penetration is commonly overlooked. Therefore, in this study, taking fluorescent labeled PL...