Modulating intestinal mucus barrier for nanoparticles penetration by surfactants

• Главные авторы: Xin Zhang (Автор), Wei Dong (Автор), Hongbo Cheng (Автор), Meixia Zhang (Автор), Yongqiang Kou (Автор), Jian Guan (Автор), Qiaoyu Liu (Автор), Mingyue Gao (Автор), Xiuhua Wang (Автор), Shirui Mao (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2019-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Improving peroral delivery efficiency is always a persistent goal for both small-molecule and macromolecular drug development. However, intestinal mucus barrier which greatly impedes drug-loaded nanoparticles penetration is commonly overlooked. Therefore, in this study, taking fluorescent labeled PL...