Docetaxel prodrug and hematoporphyrin co-assembled nanoparticles for anti-tumor combination of chemotherapy and photodynamic therapy

• Main Authors: Guolian Ren (Author), Yujie Li (Author), Canqi Ping (Author), Danyu Duan (Author), Ning Li (Author), Jiaqi Tang (Author), Rongrong Wang (Author), Wenju Guo (Author), Xiaomin Niu (Author), Qiuyue Ji (Author), Guoshun Zhang (Author), Ruili Wang (Author), Shuqiu Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To realize the synergistic anti-tumor effect of chemotherapy and photodynamic therapy, the mono sulfide-modified docetaxel (DTX) prodrugs (DSD) provided by our laboratory and hematoporphyrin (HP) were used to physically prepare co-assembled nanoparticles (DSD/HP NPs) by nano-precipitation. For the f...