Recombinant Erythropoietin Provides Protection against Renal Fibrosis in Adenine-Induced Chronic Kidney Disease

• Main Authors: Estefanía Vázquez-Méndez (Author), Yanet Gutiérrez-Mercado (Author), Edgar Mendieta-Condado (Author), Francisco Javier Gálvez-Gastélum (Author), Hugo Esquivel-Solís (Author), Yadira Sánchez-Toscano (Author), Claudia Morales-Martínez (Author), Alejandro A. Canales-Aguirre (Author), Ana Laura Márquez-Aguirre (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic kidney disease (CKD) causes anemia by renal damage. In CKD, the kidney is submitted to hypoxia, persistent inflammation, leading to fibrosis and permanent loss of renal function. Human recombinant erythropoietin (rEPO) has been widely used to treat CKD-associated anemia and is known to posse...