2-O-Acyl-3-O-(1-acyloxyalkyl) Prodrugs of 5,6-Isopropylidene-l-Ascorbic Acid and l-Ascorbic Acid: Antioxidant Activity and Ability to Permeate Silicone Membranes

• Hauptverfasser: Nikki A. Thiele (Verfasst von), Jennifer McGowan (Verfasst von), Kenneth B. Sloan (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2016-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

2-O-Acyl-3-O-(1-acyloxyalkyl) prodrug derivatives, 15, of 5,6-isopropylidene-l-ascorbic acid, VCA, and l-ascorbic acid, VC, have been characterized by measuring (1) their solubilities in water (SAQ) and in 1-octanol (SOCT); (2) the ability of one member of the homologous series, 15a, to diffuse thro...